MDASI Spine Tumor Module
The MD Anderson Symptom Inventory for spine tumors (MDASI-SP) is a site-specific module. Use the MDASI-SP to assess the severity of symptoms experienced by patients with spine tumors and the interference with daily living caused by these symptoms.
Along with the core MDASI’s 13 symptom items and 6 interference items, the MDASI-SP also assesses 5 symptoms specific to spine tumors.
| Core MDASI Symptom Items | Spine Tumor Symptom Items | MDASI Interference Items |
|---|---|---|
| Pain | Radiating spine pain | Relations with other people |
| Fatigue | Weakness in arms or legs | Enjoyment of life |
| Nausea | Sexual dysfunction | Mood |
| Disturbed sleep | Change in bowel pattern (diarrhea or constipation) | Walking |
| Distress (feeling upset) | Loss of control of bowel and/or bladder | Activity |
| Shortness of breath | Work (including housework) | |
| Difficulty remembering | ||
| Lack of appetite | ||
| Drowsiness | ||
| Dry mouth | ||
| Sadness | ||
| Vomiting | ||
| Numbness/tingling |
MDASI-SP Features
- Purpose: To assess the severity of multiple spine tumor-related symptoms and the impact of these symptoms on daily functioning
- Population: Patients with symptoms caused by spine tumors and their treatment
- Assessment areas: Severity of multiple symptoms and the impact of symptoms on daily functioning during the last 24 hours
- Method: Self-report or interview with research staff; paper-and-pencil or electronic data entry
- Time required: Five minutes or less
- Scoring: Please see the MDASI User Guide
- Reliability: Cronbach alpha reliability ranges from 0.71 to 0.95
View the MDASI-SP (click to enlarge)
MDASI-SP Language Translations
Don't see a language you need? Contact us at symptomresearch@mdanderson.org.
| Psychometrically and Linguistically Validated | Linguistically Validated |
|---|---|
| English |
MDASI User Guide
In response to the for the pharmaceutical industry on the use of patient-reported outcomes measures in medical product development to support labeling claims, we have prepared a MDASI User Guide to document the development and psychometric properties of the MDASI and its modules, including the MDASI-AML/MDS. The User Guide addresses the recommendations in the FDA guidance and establishes the MDASI's adequacy as a measure to support medical product claims.
Request a copy of the MDASI User Guide.
Selected MDASI-SP References
Validation
Xu N, Li Z, Wei F, et al. J Pain Symptom Manage 53(3):605-613, 2017.
Armstrong TS, Gning I, Mendoza TR, et al. J Neurosurg Spine 12(4):421-430, 2010.
Cleeland CS, Mendoza TR, Wang XS, et al. Cancer 89:1634-1646, 2000.
Clinical Application
Rogers JL, Vera E, Acquaye A, et al. Neurooncol Pract 8(4):460-474, 2021.
Newman WC, Berry-Candelario J, Villavieja J, et al. Neurosurgery 88(5):989-995, 2021.
Gilbert MR, Yuan Y, Wu J, et al. Neuro Oncol 23(3):468-477, 2021.
Barzilai O, McLaughlin L, Amato MK, et al. Spine J 18(7):1109-1115, 2018.
Methodology
Rothrock RJ, Reiner AS, Barzilai O, et al. Neurosurgery 91(4):604-617, 2022.
Hussain I, Barzilai O, Reiner AS, et al. J Neurosurg Spine 18:1-7, 2019.
Barzilai O, Amato MK, McLaughlin L, et al. Neurooncol Pract 5(2):104-113, 2018.
Hussain I, Barzilai O, Reiner AS, et al. Spine J 18(2):261-267, 2018.
Order the MDASI-SP
Use our convenient online form to order the MDASI-SP for use in your clinical research, clinical practice, funded and non-funded academic research, commercial research, or reproduction in educational materials or other publications.
Did You Know?
Electronic data capture offers several benefits:
- Allows symptom monitoring when the patient is away from the hospital
- Is convenient for patients, who can choose web access, personalized patient portals, or smartphones to access questionnaires
- Minimizes missing data, especially in longitudinal studies
- Provides accurate, real-time symptom data at expected time points
- Generates immediate feedback, potentially allowing caregivers to address severe symptoms more effectively
Cancer patients with central nervous system tumors are a unique group because of the neurological nature of their symptoms, which affect their functional abilities, social interactions and emotional well-being — and thus their quality of life.
Terri S. Armstrong, Ph.D.
Senior Investigator, NCI
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Research Areas
Find out about the four types of research taking place at UT?MD Anderson.