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Soluble E-cadherin¨CCXCL1¨CCXCR2 Axis as a Therapeutic Vulnerability in Inflammatory Breast Cancer Brain Metastasis. Hu X, Xiong Y, Villodre ES, Longa IR, Song J, Fowlkes N, Krishnamurthy S, Rylander M, Bartholomeusz C, Tripathy D, Woodward WA, Chen J, Debeb BG. Neuro-Oncology 2026. doi:

Serum S100A8/S100A9 is associated with increased risk of brain metastasis in patients with inflammatory breast cancer. Villodre ES, Song J, Hu X, Gomes K, Cohen EN, Reuben JM, Nasrazadani A, Lim B, UT MD Anderson Inflammatory Breast Cancer Team, Tripathy T, Woodward A, Krishnamurthy S, Debeb BG. medRxiv [Preprint]. 2026 Jan 22:2026.01.21.26344294. doi: .

Retrospective review of metastatic hormone receptor-positive inflammatory breast cancer patients reveals poor responses to cyclin dependent kinase 4/6 inhibition. Nasrazadani A, Tidwell RS, Kai M, Lim B, Valero V, Tripathy D, Saleem S, Debeb BG, Lucci A, Woodward WA, Layman RM, UT MD Anderson IBC Clinic and Research Team. Breast Cancer Research, 2025 Dec 10;28(1):8. doi:

Soluble E-cadherin Drives Brain Metastasis in Inflammatory Breast Cancer. Hu X, Xiong Y, Villodre ES, Zhang H, Song J, Fowlkes N, Krishnamurthy S, Rylander M, Bartholomeusz C, Tripathy D; MD Anderson Inflammatory Breast Cancer Team; Woodward WA, Chen J, Debeb BG. bioRxiv [Preprint]. 2025 Jun 24:2025.06.18.660428. doi:

Inhibition of MCL-1 and MEK Overcomes MEK Inhibitor Resistance in Triple-Negative and Inflammatory Breast Cancers. Mughees M, Tacam M, Tan AW, Pitner MK, Iles LR, Hu X, Villodre ES, Debeb BG, Kogawa T, Lim B, Layman RM, Woodward WA, Ueno NT, Tripathy D, Krishnamurthy S, Qi Y, Pusztai L, Wang J, Gandhi V, Bartholomeusz G, Bartholomeusz C. Mol Cancer Ther. 2025 Sep 2;24(9):1453-1465. doi:

NDRGs in Breast Cancer: A Review and In Silico Analysis. Villodre ES, Nguyen APN, Debeb BG. Cancers (Basel). 2024 Mar 29;16(7):1342. doi:

In Vivo Simvastatin and Brain Radiation in a Model of HER2+ Inflammatory Breast Cancer Brain Metastasis. Kumar S, Larson RA, Stecklein S, Reddy J, Debeb BG, Amos RA, Cologna SM, Woodward WA. bioRxiv [Preprint]. 2024 May 30:2024.05.25.595905. doi:

Genome-wide CRISPR screen reveals the synthetic lethality between BCL2L1 inhibition and radiotherapy. Yin L, Hu X, Pei G, Tang M, Zhou Y, Zhang H, Huang M, Li S, Zhang J, Citu C, Zhao Z, Debeb BG, Feng X, Chen J. Life Sci Alliance. 2024 Feb 5;7(4): e202302353. doi:

High-fat diet, but not duration of lactation, increases mammary gland lymphatic vessel function and subsequent growth of inflammatory breast cancer cells. Balema W, Morton J, Larson RA, Li L, Velasquez FC, Fowlkes NW, Krishnamurthy S, Debeb BG, Sevick-Muraca E, Woodward WA. J Mammary Gland Biol Neoplasia. 2023 Oct 6;28(1):21. doi:   

Influence of Macrophages on Vascular Invasion of Inflammatory Breast Cancer Emboli Measured Using an In Vitro Microfluidic Multi-Cellular Platform. Gadde M, Mehrabi Dehdezi M, Debeb BG, Woodward WA, Rylander MN. Cancers (Basel). 2023 Oct 8;15(19):4883. doi:

Response to de Nonneville, Finetti, Mamessier, and Bertucci. Villodre ES, Hu X, Huo L, Debeb BG. J Natl Cancer Inst. 2022 Jul 11;114(7):1048-1049. doi:

NDRG1 in Aggressive Breast Cancer Progression and Brain Metastasis. Villodre ES, Hu X, Eckhardt BL, Larson R, Huo L, Yoon EC, Gong Y, Song J, Liu S, Ueno NT, Krishnamurthy S, Pusch S, Tripathy D, Woodward WA, Debeb BG. Journal of the National Cancer Institute, 2021; djab222, DOI: 

Inflammatory breast cancer appearance at presentation is associated with overall survival. Balema W, Liu D, Shen Y, El-Zein R, Debeb BG, Kai M, Overmoyer B, Miller KD, Le-Petross HT, Ueno NT, Woodward WA. Cancer Med. e-Pub 2021. PMCID: 

Lipocalin 2 promotes inflammatory breast cancer tumorigenesis and skin invasion. Villodre ES, Hu X, Larson R, Finetti P, Gomez K, Balema W, Stecklein SR, Santiago-S¨¢nchez GS, Krishnamurthy S, Song J, Su X, Ueno NT, Tripathy T, Van Laere S, Bertucci F, Vivas-Mej¨ªa P, Woodward WA, Debeb BG. Molecular Oncology, 2021.  PMCID: 

Targeting Lipocalin-2 in inflammatory breast cancer cells with small interference RNA and small molecule inhibitors. Santiago-S¨¢nchez GS, Noriega-Rivera R, Hern¨¢ndez-O¡¯Farrill E, Valiyeva F, Qui?ones-Diaz B, Villodre ES, Debeb BG, Rosado-Albacarys A, Vivas-Mej¨ªa PE. International Journal of Molecular Sciences, 22, 8581, 2021. PMCID: 

Modeling Brain Metastasis Via Tail-Vein Injection of Inflammatory Breast Cancer Cells. Hu X*, Villodre ES*, Woodward WA, Debeb BG. J. Vis. Exp., 168, e62249, 2021. DOI: 

Multi-omic molecular profiling reveals potentially targetable abnormalities shared across multiple histologies of brain metastasis. Fukumura K, Malgulwar PB, Fischer GM, Hu X, Mao X, Song X, Hernandez SD, Zhang XH, Zhang J, Parra ER, Yu D, Debeb BG, Davies MA, Huse JT. Acta Neuropathol 141(2):303-321, 2/2021. DOI: 

Decorin-mediated suppression of tumorigenesis, invasion, and metastasis in inflammatory breast cancer. Hu X, Villodre ES, Larson R, Rahal OM, Wang X, Gong Y, Song J, Krishnamurthy S, Ueno NT, Tripathy D, Woodward WA, Debeb BG. Communications Biology, 4, 72, 2021. PMCID: 

Prophylactic cranial irradiation reduces the incidence of brain metastasis in a mouse model of metastatic, HER2-positive breast cancer. Smith DL, Debeb BG, Diagaradjane P, Larson R, Kumar S, Ning J, Lacerda L, Li L, Woodward WA. Genes Cancer 12:28-38, 2021. PMCID: 

NDRG1 expression is an independent prognostic factor in inflammatory breast cancer. Villodre ES, Gong Y, Hu X, Huo L, Yoon EC, Ueno NT, Woodward WA, Tripathy D, Song J, Debeb BG. Cancers, 12, 3711, 2020.  PMCID: 

Differential functions of ERK1 and ERK2 in lung metastasis processes in triple-negative breast cancer. Gagliardi M, Pitner MK, Park J, Xie X, Saso H, Larson RA, Sammons RM, Chen H, Wei C, Masuda H, Chauhan G, Kondo K, Tripathy D, Ueno NT, Dalby KN, Debeb BG, Bartholomeusz C. Sci Rep 10(1):8537; 2020; PMCID: 

NOTCH and DNA repair pathways are more frequently targeted by genomic alterations in inflammatory than in non-inflammatory breast cancers. Bertucci F, Rypens C, Finetti P, Guille A, Ad¨¦la?de J, Monneur A, Carbuccia N, Garnier S, Dirix P, Gon?alves A, Vermeulen P, Debeb BG, Wang X, Dirix L, Ueno NT, Viens P, Cristofanilli M, Chaffanet M, Birnbaum D, Van Laere S. Mol Oncol 14(3):504-519; 2020 PMCID: