911±¬ÁÏ- ÿÈÕ³Ô¹ÏÇ鱨վ

Executive Director, MWIBC
Breast Radiation Oncology

Learn more about the Woodward Lab

Woodward's work focuses upon:

• Providing conformal radiation therapy for patients with IBC
• Characterizing radiation resistance in IBC stem cells
• Examining mechanisms of sensitizing IBC to radiation including targeting stem cell signaling pathways, signaling and epithelial mesenchymal transition (EMT) in IBC cells and tumor models

Deputy Director, MWIBC
Breast Surgical Oncology

Learn more about the Lucci Lab

Lucci's work focuses upon:

• Investigating targetable networks in the aggressive sub-populations of IBC cells and metabolism in IBC
• Developing new laboratory-based assays to evaluate novel therapies against IBC
• Evaluating novel therapies in xenograft mouse models of IBC
• Determining the DTC and CTC status of IBC patients
• Maintaining a database of test results and outcomes of IBC patients
• Investigating the molecular characteristics of DTCs and CTCs from IBC patients

Director, Clinical Operations
Breast Medical Oncology

Valero's work focuses upon:

• Investigating breast neoplasms, unusual histologies, new drug development and clinical trials targeting health disparities
• Her-2 neu amplified and ER+ HER-2 normal early, as well as metastatic breast cancers

Director, Clinical Research
Breast Medical Oncology

Layman's work focuses upon:

• Understanding the biology of ER+ breast cancer including IBC
• Development of novel therapeutic clinical trials

Director, Translational Research
Breast Medical Oncology

 Lim¡¯s work focuses upon:

• Single cell/Spatial genomics of IBC
• Determining tumor-immune ecosystem of IBC and therapeutic opportunity
• ctDNA guided MRD targeting and tailoring of systemic therapy
• Next generation immune targeting in IBC
• Integration of multiomic data in IBC

Breast Pathology

Krishnamurthy's work focuses upon:

• Investigating molecular and biologic markers in IBC
• Providing laboratory support through tissue specimen preparation, interpretation and ancillary techniques, including immunohistochemistry and in situ hybridization

Breast Imaging

Le-Petross's work focuses upon:

• Evaluating the utility of contrast-enhanced magnetic resonance (MR) imaging and advanced MR imaging techniques, such as MR spectroscopy and MR diffusion-weighted imaging, in IBC patients at the initial staging and for therapy response assessment

Breast Medical Oncology

Nasrazadani¡¯s work focuses upon:

• In-depth analysis of IBC patient registry data to identify critical patterns and comprehensive characterization of IBC natural history 
• Identifying IBC subpopulations at risk of CNS metastasis through targeted analysis
• Understanding resistance mechanisms underlying hormone receptor positive metastatic IBC
• Understanding the elusive biology of inflammatory invasive lobular carcinoma
• Developing clinical trials in the adjuvant setting targeting patients with elevated risk of CNS relapse

Breast Radiation Oncology

Goodman¡¯s work focuses upon:

• Circulating tumor material as a biomarker for radiation selection
• Artificial intelligence approaches to diagnose IBC on MRI
• Patient education

Plastic Surgery

Schaverien's work focuses upon:

• Optimization of autologous reconstruction outcomes for patients with IBC
• Prevention and treatment of lymphedema through microsurgical approaches at the time of mastectomy and concurrently with reconstruction

Breast Pathology

Gong's work focuses upon:

• Providing tissue banking from IBC patients who are diagnosed and/or treated at UT MD Anderson
• Performing pathologic (morphologic and immunohistochemical) evaluation on IBC-related projects

Breast Pathology

 Huo's work focuses upon:

• Correlation between clinicopathologic factors and outcome in IBC
• Understanding the molecular mechanisms of IBC through microRNA expression

Breast Radiation Oncology

Stauder's work focuses upon:

• Providing tailored radiation plans to IBC patients
• Evaluating outcomes of IBC patients receiving radiation

Breast Surgical Oncology

Sun's work focuses upon:

• Surgical management of IBC and lymphedema management
• Cost-effectiveness studies of patient treatments

Breast Imaging

Whitman's work focuses upon:

• Optimization of breast imaging for detection and evaluation of IBC, including mammography, ultrasound and MRI
• Evaluation of screening approaches to IBC
• High-risk screening modalities
• IBC with lobular features

IBC Scientist
Discipline Leader
Breast Medical Oncology

Learn more about the Bartholomeusz Lab

Bartholomeusz's work focuses upon:

• Understanding kinase biology, identifying and validating novel kinase inhibitors and developing these agents into clinical strategies for patients with TNBC and IBC
  
• Characterizing the role of MAPK-PEA-15 signaling in triple-negative/inflammatory breast cancer (IBC) in EMT, CSC and metastasis and validating this pathway as a target
  
• Examining mechanisms of drug resistance resulting in recurrence of disease in TNBC and IBC

IBC Scientist
Breast Medical Oncology

Learn more about the Debeb Lab

Debeb's work focuses upon:

• Identifying and targeting the functional drivers of brain metastases in IBC 
• Developing preclinical models of brain metastasis in IBC 
• Developing novel biomarkers for IBC patients at high risk of developing brain metastasis
• Understanding the unique pathobiology of IBC aggressiveness
• Elucidating cancer cell plasticity and the role of cancer stem cells in mediating therapy resistance, recurrence and metastasis

IBC Houston Area Locations (HAL) Lead
General Oncology